Effectiveness of aloe vera in patients with type 2 Diabetes Mellitus and pre-diabetes: An overview of systematic reviews

Felipe Araya-Quintanilla; Héctor Gutiérrez-Espinoza; Iván Cuyul-Vásquez; Leonardo Pavez

doi:10.1016/j.dsx.2021.102292

Effectiveness of aloe vera in patients with type 2 Diabetes Mellitus and pre-diabetes: An overview of systematic reviews

Felipe Araya-Quintanilla, Héctor Gutiérrez-Espinoza, Iván Cuyul-Vásquez, Leonardo Pavez

Facultad de Medicina Veterinaria y Agronomía

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Background and aims: The effects of aloe vera are inconsistent and unclear. The aim of this study is to analyze the effects of aloe vera in metabolic profiles. Methods: An electronic search of systematic reviews (SRs) was performed in seven databases up to June 2021. Results: Four SRs met the eligibility criteria. In T2DM, SMD for FBG = −5.61 (p < 0.001). For HbA1c, MD = −0.95 (p = 0.02). In pre-diabetes, SMD for FBG = −1.41 (p = 0.02). For HbA1c, MD = −0.31 (p = 0.02). For TG, MD = −4.99 (p = 0.000). Conclusion: There exist a moderate to high quality of evidence in favor of the effects of aloe vera in patients with T2DM and pre-diabetes.

Original language	English
Article number	102292
Journal	Diabetes and Metabolic Syndrome: Clinical Research and Reviews
Volume	15
Issue number	6
DOIs	https://doi.org/10.1016/j.dsx.2021.102292
State	Published - 1 Nov 2021

Keywords

Aloe vera
Diabetes mellitus
Fasting blood glucose
Overview
Systematic review

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.dsx.2021.102292

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title = "Effectiveness of aloe vera in patients with type 2 Diabetes Mellitus and pre-diabetes: An overview of systematic reviews",

abstract = "Background and aims: The effects of aloe vera are inconsistent and unclear. The aim of this study is to analyze the effects of aloe vera in metabolic profiles. Methods: An electronic search of systematic reviews (SRs) was performed in seven databases up to June 2021. Results: Four SRs met the eligibility criteria. In T2DM, SMD for FBG = −5.61 (p < 0.001). For HbA1c, MD = −0.95 (p = 0.02). In pre-diabetes, SMD for FBG = −1.41 (p = 0.02). For HbA1c, MD = −0.31 (p = 0.02). For TG, MD = −4.99 (p = 0.000). Conclusion: There exist a moderate to high quality of evidence in favor of the effects of aloe vera in patients with T2DM and pre-diabetes.",

keywords = "Aloe vera, Diabetes mellitus, Fasting blood glucose, Overview, Systematic review",

author = "Felipe Araya-Quintanilla and H{\'e}ctor Guti{\'e}rrez-Espinoza and Iv{\'a}n Cuyul-V{\'a}squez and Leonardo Pavez",

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doi = "10.1016/j.dsx.2021.102292",

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Effectiveness of aloe vera in patients with type 2 Diabetes Mellitus and pre-diabetes: An overview of systematic reviews. / Araya-Quintanilla, Felipe; Gutiérrez-Espinoza, Héctor; Cuyul-Vásquez, Iván et al.
In: Diabetes and Metabolic Syndrome: Clinical Research and Reviews, Vol. 15, No. 6, 102292, 01.11.2021.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Effectiveness of aloe vera in patients with type 2 Diabetes Mellitus and pre-diabetes

T2 - An overview of systematic reviews

AU - Araya-Quintanilla, Felipe

AU - Gutiérrez-Espinoza, Héctor

AU - Cuyul-Vásquez, Iván

AU - Pavez, Leonardo

PY - 2021/11/1

Y1 - 2021/11/1

N2 - Background and aims: The effects of aloe vera are inconsistent and unclear. The aim of this study is to analyze the effects of aloe vera in metabolic profiles. Methods: An electronic search of systematic reviews (SRs) was performed in seven databases up to June 2021. Results: Four SRs met the eligibility criteria. In T2DM, SMD for FBG = −5.61 (p < 0.001). For HbA1c, MD = −0.95 (p = 0.02). In pre-diabetes, SMD for FBG = −1.41 (p = 0.02). For HbA1c, MD = −0.31 (p = 0.02). For TG, MD = −4.99 (p = 0.000). Conclusion: There exist a moderate to high quality of evidence in favor of the effects of aloe vera in patients with T2DM and pre-diabetes.

AB - Background and aims: The effects of aloe vera are inconsistent and unclear. The aim of this study is to analyze the effects of aloe vera in metabolic profiles. Methods: An electronic search of systematic reviews (SRs) was performed in seven databases up to June 2021. Results: Four SRs met the eligibility criteria. In T2DM, SMD for FBG = −5.61 (p < 0.001). For HbA1c, MD = −0.95 (p = 0.02). In pre-diabetes, SMD for FBG = −1.41 (p = 0.02). For HbA1c, MD = −0.31 (p = 0.02). For TG, MD = −4.99 (p = 0.000). Conclusion: There exist a moderate to high quality of evidence in favor of the effects of aloe vera in patients with T2DM and pre-diabetes.

KW - Aloe vera

KW - Diabetes mellitus

KW - Fasting blood glucose

KW - Overview

KW - Systematic review

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DO - 10.1016/j.dsx.2021.102292

M3 - Review article

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SN - 1871-4021

VL - 15

JO - Diabetes and Metabolic Syndrome: Clinical Research and Reviews

JF - Diabetes and Metabolic Syndrome: Clinical Research and Reviews

IS - 6

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ER -

Effectiveness of aloe vera in patients with type 2 Diabetes Mellitus and pre-diabetes: An overview of systematic reviews

Abstract

Keywords

UN SDGs

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