>Rol del ligando del factor nuclear kappa Beta (RANKL) en osteoartritis y osteoclastogénesis de equinos fina sangre de carrera. Uso de antiinflamatorios

Translated title of the contribution: Role of the nuclear factor kappa Beta ligand (RANKL) in osteoarthritis and oseteoclastogenesis in thoroughbred horses. Use of anti-inflammatory drugs

Luis De Negri, Luis Olguin, Leonardo Pavez

Research output: Contribution to journalArticlepeer-review

Abstract

Osteoarthritis (OA) is one of the main conditions that affects the performance of sports horses. Early diagnosis of the disease is relevant in its clinical and therapeutic management. The evidence shows that this process has a clear relationship between osteoclasts and immune cells sharing molecules such as cytokines, receptors, signaling molecules and transcription factors that influence each other where they play a crucial role in both pathological and physiological bone resorption. The role of the nuclear receptor activator ligand kβ (RANKL) is described as one of the most relevant cytokines that induce osteoclastogenesis.

Translated title of the contributionRole of the nuclear factor kappa Beta ligand (RANKL) in osteoarthritis and oseteoclastogenesis in thoroughbred horses. Use of anti-inflammatory drugs
Original languageSpanish
Article numbere20009
JournalRevista de Investigaciones Veterinarias del Peru
Volume32
Issue number2
DOIs
StatePublished - 23 Apr 2021

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