Maximizing Haematococcus biorefineries: Ionic liquid-based astaxanthin recovery, biocosmetic formulation, solar cell applications, and biofertilizer valorization

Cassamo U. Mussagy; Angie V. Caicedo-Paz; Debora Figueroa; Christian Santander; Felipe González; Alessia Tropea; Luigi Mondello; Donatella Spadaro; Stefano Trocino; Rodolfo D. Piazza; Rodrigo F.C. Marques; Karina Godoy; Pablo Cornejo

doi:10.1016/j.biortech.2025.132347

Maximizing Haematococcus biorefineries: Ionic liquid-based astaxanthin recovery, biocosmetic formulation, solar cell applications, and biofertilizer valorization

Cassamo U. Mussagy, Angie V. Caicedo-Paz, Debora Figueroa, Christian Santander, Felipe González, Alessia Tropea, Luigi Mondello, Donatella Spadaro, Stefano Trocino, Rodolfo D. Piazza, Rodrigo F.C. Marques, Karina Godoy, Pablo Cornejo

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Microalgae, particularly Haematococcus pluvialis, produce astaxanthin (AXT), a potent antioxidant with growing potential in the food, pharmaceutical, biocosmetic, and renewable energy sectors. This study proposes an integrated biorefinery model that employs advanced extraction processes, including bio-based ionic liquids, to efficiently recover AXT from H. pluvialis while minimizing environmental impact. The resulting platform strategically repurposes the post-extraction biomass as a biofertilizer, thus contributing to zero-waste objectives. By uniting biocosmetics, solar energy applications, and agriculture within a single framework, this model underscores the synergy between economic feasibility and ecological responsibility, highlighting the transformative role of microbial-derived AXT in sustainable, high-value product development.

Original language	English
Article number	132347
Journal	Bioresource Technology
Volume	426
DOIs	https://doi.org/10.1016/j.biortech.2025.132347
State	Published - Jun 2025
Externally published	Yes

Keywords

Bioprocessing integration
Haematococcus pluvialis
Microalgae
Neoteric solvents

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.biortech.2025.132347

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Mussagy, C. U., Caicedo-Paz, A. V., Figueroa, D., Santander, C., González, F., Tropea, A., Mondello, L., Spadaro, D., Trocino, S., Piazza, R. D., Marques, R. F. C., Godoy, K., & Cornejo, P. (2025). Maximizing Haematococcus biorefineries: Ionic liquid-based astaxanthin recovery, biocosmetic formulation, solar cell applications, and biofertilizer valorization. Bioresource Technology, 426, Article 132347. https://doi.org/10.1016/j.biortech.2025.132347

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title = "Maximizing Haematococcus biorefineries: Ionic liquid-based astaxanthin recovery, biocosmetic formulation, solar cell applications, and biofertilizer valorization",

abstract = "Microalgae, particularly Haematococcus pluvialis, produce astaxanthin (AXT), a potent antioxidant with growing potential in the food, pharmaceutical, biocosmetic, and renewable energy sectors. This study proposes an integrated biorefinery model that employs advanced extraction processes, including bio-based ionic liquids, to efficiently recover AXT from H. pluvialis while minimizing environmental impact. The resulting platform strategically repurposes the post-extraction biomass as a biofertilizer, thus contributing to zero-waste objectives. By uniting biocosmetics, solar energy applications, and agriculture within a single framework, this model underscores the synergy between economic feasibility and ecological responsibility, highlighting the transformative role of microbial-derived AXT in sustainable, high-value product development.",

keywords = "Bioprocessing integration, Haematococcus pluvialis, Microalgae, Neoteric solvents",

author = "Mussagy, {Cassamo U.} and Caicedo-Paz, {Angie V.} and Debora Figueroa and Christian Santander and Felipe Gonz{\'a}lez and Alessia Tropea and Luigi Mondello and Donatella Spadaro and Stefano Trocino and Piazza, {Rodolfo D.} and Marques, {Rodrigo F.C.} and Karina Godoy and Pablo Cornejo",

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year = "2025",

month = jun,

doi = "10.1016/j.biortech.2025.132347",

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Mussagy, CU, Caicedo-Paz, AV, Figueroa, D, Santander, C, González, F, Tropea, A, Mondello, L, Spadaro, D, Trocino, S, Piazza, RD, Marques, RFC, Godoy, K & Cornejo, P 2025, 'Maximizing Haematococcus biorefineries: Ionic liquid-based astaxanthin recovery, biocosmetic formulation, solar cell applications, and biofertilizer valorization', Bioresource Technology, vol. 426, 132347. https://doi.org/10.1016/j.biortech.2025.132347

TY - JOUR

T1 - Maximizing Haematococcus biorefineries

T2 - Ionic liquid-based astaxanthin recovery, biocosmetic formulation, solar cell applications, and biofertilizer valorization

AU - Mussagy, Cassamo U.

AU - Caicedo-Paz, Angie V.

AU - Figueroa, Debora

AU - Santander, Christian

AU - González, Felipe

AU - Tropea, Alessia

AU - Mondello, Luigi

AU - Spadaro, Donatella

AU - Trocino, Stefano

AU - Piazza, Rodolfo D.

AU - Marques, Rodrigo F.C.

AU - Godoy, Karina

AU - Cornejo, Pablo

PY - 2025/6

Y1 - 2025/6

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AB - Microalgae, particularly Haematococcus pluvialis, produce astaxanthin (AXT), a potent antioxidant with growing potential in the food, pharmaceutical, biocosmetic, and renewable energy sectors. This study proposes an integrated biorefinery model that employs advanced extraction processes, including bio-based ionic liquids, to efficiently recover AXT from H. pluvialis while minimizing environmental impact. The resulting platform strategically repurposes the post-extraction biomass as a biofertilizer, thus contributing to zero-waste objectives. By uniting biocosmetics, solar energy applications, and agriculture within a single framework, this model underscores the synergy between economic feasibility and ecological responsibility, highlighting the transformative role of microbial-derived AXT in sustainable, high-value product development.

KW - Bioprocessing integration

KW - Haematococcus pluvialis

KW - Microalgae

KW - Neoteric solvents

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DO - 10.1016/j.biortech.2025.132347

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AN - SCOPUS:86000472134

SN - 0960-8524

VL - 426

JO - Bioresource Technology

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ER -

Maximizing Haematococcus biorefineries: Ionic liquid-based astaxanthin recovery, biocosmetic formulation, solar cell applications, and biofertilizer valorization

Abstract

Keywords

UN SDGs

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