A new subtle and integrated detector to sense Hg2+ ions: A vision towards its applicability on water samples and live cells

Venkatachalam Kavitha; Periasamy Viswanathamurthi; Jebiti Haribabu; Cesar Echeverria

doi:10.1016/j.jphotochem.2022.113863

A new subtle and integrated detector to sense Hg²⁺ ions: A vision towards its applicability on water samples and live cells

Venkatachalam Kavitha, Periasamy Viswanathamurthi, Jebiti Haribabu, Cesar Echeverria

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

A facile and efficient optical fluorescent probe [(2,2′-((propane-2,2-diylbis(6-vinyloxy)-3,1-(phenylene))bis(methaneylylidene))dimalanonitrile] (BMC) was designed and synthesized to sense Hg²⁺ ions via intramolecular cyclization process. The synthesized probe BMC exhibits a selective and sensitive absorption and emission wavelength for Hg²⁺ ions in presence of other competitive ions with the LOD of 18.4 nM. The control compound BM was also synthesized and the spectral properties were compared with BMC + Hg²⁺ ions solution. Moreover, the excellent specificity nature of the probe BMC contributes its usage towards the detection of Hg²⁺ ions in real samples and live HeLa cancer cells visualization.

Original language	English
Article number	113863
Journal	Journal of Photochemistry and Photobiology A: Chemistry
Volume	428
DOIs	https://doi.org/10.1016/j.jphotochem.2022.113863
State	Published - 1 Jun 2022
Externally published	Yes

Keywords

HeLa cancer cells
Hg ions
Intramolecular cyclization
Real samples
Sensitive absorption

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.jphotochem.2022.113863

Cite this

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title = "A new subtle and integrated detector to sense Hg2+ ions: A vision towards its applicability on water samples and live cells",

abstract = "A facile and efficient optical fluorescent probe [(2,2′-((propane-2,2-diylbis(6-vinyloxy)-3,1-(phenylene))bis(methaneylylidene))dimalanonitrile] (BMC) was designed and synthesized to sense Hg2+ ions via intramolecular cyclization process. The synthesized probe BMC exhibits a selective and sensitive absorption and emission wavelength for Hg2+ ions in presence of other competitive ions with the LOD of 18.4 nM. The control compound BM was also synthesized and the spectral properties were compared with BMC + Hg2+ ions solution. Moreover, the excellent specificity nature of the probe BMC contributes its usage towards the detection of Hg2+ ions in real samples and live HeLa cancer cells visualization.",

keywords = "HeLa cancer cells, Hg ions, Intramolecular cyclization, Real samples, Sensitive absorption",

author = "Venkatachalam Kavitha and Periasamy Viswanathamurthi and Jebiti Haribabu and Cesar Echeverria",

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doi = "10.1016/j.jphotochem.2022.113863",

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T1 - A new subtle and integrated detector to sense Hg2+ ions

T2 - A vision towards its applicability on water samples and live cells

AU - Kavitha, Venkatachalam

AU - Viswanathamurthi, Periasamy

AU - Haribabu, Jebiti

AU - Echeverria, Cesar

PY - 2022/6/1

Y1 - 2022/6/1

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AB - A facile and efficient optical fluorescent probe [(2,2′-((propane-2,2-diylbis(6-vinyloxy)-3,1-(phenylene))bis(methaneylylidene))dimalanonitrile] (BMC) was designed and synthesized to sense Hg2+ ions via intramolecular cyclization process. The synthesized probe BMC exhibits a selective and sensitive absorption and emission wavelength for Hg2+ ions in presence of other competitive ions with the LOD of 18.4 nM. The control compound BM was also synthesized and the spectral properties were compared with BMC + Hg2+ ions solution. Moreover, the excellent specificity nature of the probe BMC contributes its usage towards the detection of Hg2+ ions in real samples and live HeLa cancer cells visualization.

KW - HeLa cancer cells

KW - Hg ions

KW - Intramolecular cyclization

KW - Real samples

KW - Sensitive absorption

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