TY - JOUR
T1 - Comparison of the First and Second Wave of Infections by SARS-CoV-2
T2 - A Retrospective and Longitudinal Study From a Primary Health Care Center in Santiago of Chile
AU - Acuña-Castillo, Claudio
AU - Inostroza-Molina, Ailen
AU - Castro, Sergio A.
AU - Molina-Cabrera, Sonia
AU - Leiva-Salcedo, Elías
AU - Riquelme, Denise
AU - Luraschi, Roberto
AU - Barrera-Avalos, Carlos
AU - Vallejos-Vidal, Eva
AU - Mella-Torres, Andrea
AU - Valdés, Daniel
AU - Torres, Claudio
AU - Maisey, Kevin
AU - Escobar, Alejandro
AU - Reyes-Cerpa, Sebastián
AU - Toro-Ascuy, Daniela
AU - Imarai, Mónica
AU - Reyes-López, Felipe E.
AU - Sandino, Ana María
N1 - Publisher Copyright:
Copyright © 2022 Acuña-Castillo, Inostroza-Molina, Castro, Molina-Cabrera, Leiva-Salcedo, Riquelme, Luraschi, Barrera-Avalos, Vallejos-Vidal, Mella-Torres, Valdés, Torres, Maisey, Escobar, Reyes-Cerpa, Toro-Ascuy, Imarai, Reyes-López and Sandino.
PY - 2022/6/30
Y1 - 2022/6/30
N2 - The current COVID-19 pandemic is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Many countries have reported the experience of at least two contagion waves, describing associated mortality rates and population behavior. The analysis of the effect of this pandemic in different localities can provide valuable information on the key factors to consider in the face of future massive infectious diseases. This work describes the first retrospective and comparative study about behavior during the first and second waves of the COVID-19 pandemic in Chile from a primary Healthcare Center. From 19,313 real-time quantitative PCR (RT-qPCR) tests assessed, the selected 1,694 positive diagnostics showed a decrease in mortality rate in the second wave (0.6%) compared with the first (4.6%). In addition, we observed that infections in the second wave were mainly in young patients with reduced comorbidities. The population with a complete vaccination schedule shows a decrease in the duration of symptoms related to the disease, and patients with more comorbidities tend to develop severe illness. This report provides evidence to partially understand the behavior and critical factors in the severity of the COVID-19 pandemic in the population of Santiago of Chile.
AB - The current COVID-19 pandemic is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Many countries have reported the experience of at least two contagion waves, describing associated mortality rates and population behavior. The analysis of the effect of this pandemic in different localities can provide valuable information on the key factors to consider in the face of future massive infectious diseases. This work describes the first retrospective and comparative study about behavior during the first and second waves of the COVID-19 pandemic in Chile from a primary Healthcare Center. From 19,313 real-time quantitative PCR (RT-qPCR) tests assessed, the selected 1,694 positive diagnostics showed a decrease in mortality rate in the second wave (0.6%) compared with the first (4.6%). In addition, we observed that infections in the second wave were mainly in young patients with reduced comorbidities. The population with a complete vaccination schedule shows a decrease in the duration of symptoms related to the disease, and patients with more comorbidities tend to develop severe illness. This report provides evidence to partially understand the behavior and critical factors in the severity of the COVID-19 pandemic in the population of Santiago of Chile.
KW - Chile
KW - COVID-19
KW - SARS-CoV-2
KW - vaccination
KW - waves of infection
UR - http://www.scopus.com/inward/record.url?scp=85134231190&partnerID=8YFLogxK
U2 - 10.3389/fpubh.2022.913519
DO - 10.3389/fpubh.2022.913519
M3 - Article
C2 - 35844873
AN - SCOPUS:85134231190
SN - 2296-2565
VL - 10
JO - Frontiers in Public Health
JF - Frontiers in Public Health
M1 - 913519
ER -
