Inhibitor-induced dimerization mediates lufotrelvir resistance in mutants of SARS-CoV-2 3C-like protease

Guanyu Wang, Felipe Venegas, Andres Rueda, Osvaldo Yañez, Manuel I. Osorio, Sibei Qin, José Manuel Pérez-Donoso, Christopher J. Thibodeaux, Nicolas Moitessier, Anthony K. Mittermaier

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Biochemistry, Genetics and Molecular Biology

Medicine and Dentistry